Ayurvedic Management of Systemic Lupus Erythematosus with Respect to Vatapradhana Vatarakta: A Case Report
CASE STUDY
Dr. Rashmi Singh
PG Scholar, Dept. of Pancakarma, ITRA, Jamnagar, https://orcid.org/0009-0007-5427-3898
Dr. Rita Khagram
Associate Professor, Dept. of Pancakarma, ITRA, Jamnagar, https://orcid.org/0009-0002-9065-9628
Ayurvedic Management of Systemic Lupus Erythematosus with Respect to Vatapradhana Vatarakta: A Case Report
International Journal of Ayurveda360 | Volume 1 | Issue 6|
Journal Details:
- ISSN (ONLINE) : 3048-7390
- ISSN (PRINT) : 3048-7382
- Bimonthly Journal
HOW TO CITE THIS ARTICLE?
Singh, R., & Khagram, R. (2025). Ayurvedic management of systemic lupus erythematosus with respect to Vatapradhana Vatarakta: A case report. International Journal of Ayurveda360, 1(6), 475-483, https://doi.org/3048-7390.vol.1.issue6.6
Manuscript Received | Review Round 1 | Review Round 2 | Review Round 3 | Final Updated Received |
11/04/2025 | 25/04/2025 | 28/04/2025 | 18/05/2025 | 11/06/2025 |
Accepted | Conflict of Interest | Funding | Ethical Approval | Plagiarism Checker |
12/06/2025 | NIL | NIL | Consent Received | 9% |
Published: 15-June-2025
DOI: 3048-7390.vol.1.issue6.6
DOI Link: https://doi.org/10.63247/3048-7390.vol.1.issue6.6
Address for Correspondence: Dr. Rashmi Singh, PG Scholar, Dept. of Pancakarma, ITRA, Jamnagar. Email: singhrashmi250841@gmail.com
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ABSTRACT
Introduction: Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disorder affecting connective tissues, where the immune system attacks healthy body tissues like skin, joints, kidneys, and other organs. Symptoms include fever, fatigue, myalgia, arthralgia, arthritis, malar rash, and oral ulcers. SLE can be correlated with Vatarakta in Ayurveda, presenting symptoms such as pain, swelling, and stiffness at multiple joints with blackish discoloration.
Objective: To explore the Ayurvedic management of Systemic Lupus Erythematosus (SLE) with reference to Vatapradhan Vatarakta.
Materials and Methods: As vitiated Vata is involved in the pathology of Vatarakta, Basti (an Ayurvedic enema therapy) is considered the most effective treatment for relieving this condition. Mridu Virechana (mild purgation) was selected before Basti to detoxify the body, considering the patient’s history of steroid use.
Results and Discussion: Both Vata and Rakta were vitiated, which contributed to the symptoms. The management plan focused on addressing both Vata and Rakta Dushti (imbalance). The detoxifying effects of Virechana were aimed at reducing the harmful impact of steroids, followed by Basti to balance Vata.
Conclusion: This case report highlights the potential of Ayurveda in managing autoimmune disorders like SLE by targeting the vitiation of Vata and Rakta through specific treatments like Basti and Virechana.
Keywords: Vatarakta, SLE, Basti, Virechana, Vatapradhan Vatarakta, Ayurveda
FULL PAPER
Introduction
Systemic Lupus Erythematosus (SLE) is a chronic, autoimmune, multisystem connective tissue disorder with a wide spectrum of clinical manifestations. It predominantly affects women of reproductive age and presents with symptoms such as fever, fatigue, myalgia, arthralgia, arthritis, malar rash, oral ulcers, and systemic involvement including renal and neurological complications. In India, its prevalence ranges from 14 to 60 per 100,000 population [1].
From the Ayurvedic perspective, the clinical features of SLE can be correlated with Vatapradhana Vatarakta, a disease resulting from the simultaneous vitiation of Vata and Rakta [2]. The aggravated Vata, obstructed by morbid Rakta, disturbs the balance of the body and gives rise to various symptoms. Vatarakta is known by several synonyms such as Khuda, Vatabalasa, and Adhyavata[3]. The term Adhyavata reflects the disease’s tendency to affect individuals with a delicate constitution (Sukumara Purusha) and those indulging in unwholesome dietetic habits and sedentary lifestyles—factors often seen in affluent populations[4].
This case report presents the Ayurvedic approach to managing a confirmed case of SLE, highlighting the diagnostic correlation with Vatapradhana Vatarakta and the effectiveness of Panchakarma and Ayurvedic medication.
Patient Information
A 32-year-old female patient presented to the Panchakarma OPD at ITRA, Jamnagar, with complaints of:
- Pain, swelling, and stiffness in bilateral hands, feet, knees, and elbows for the past 3 years
- Blackish discoloration over affected joints
- Intermittent episodes of fever for the past 3 years
- Anxiety symptoms for the past 4 years
She had a known history of Hypertension (2 years) and had tested ANA positive in 2022. Her allopathic treatment included Hydroxychloroquine (HCQ) and Prednisolone for SLE, and Telmisartan 20 mg daily for hypertension. The patient was admitted to the female ward of the Panchakarma Department at ITRA, Jamnagar for Ayurvedic management. Informed consent was obtained before initiating examination and therapy.
Clinical Findings
Table No. 1 : General Examination
Parameter |
Value |
Pulse Rate |
67/min |
Heart Rate |
70 beats/min |
Respiratory Rate |
16 breaths/min |
Blood Pressure |
130/80 mmHg |
Body Temperature |
99.6 °F |
Table No. 2 : Pain Assessment (VAS Score)
Joint |
VAS Score (0–10) |
Bilateral Elbow |
9 |
Bilateral Hands |
9 |
Bilateral Feet |
10 |
Bilateral Knees |
10 |
Table No. 3 : Stiffness Assessment
Stiffness Grade |
Description |
Score (BT) |
0 |
No stiffness |
0 |
1 |
Mild (can perform daily activities) |
0 |
2 |
Moderate (difficulty performing daily routine) |
0 |
3 |
Severe (unable to perform daily activities) |
3 |
Table No. 4 : Swelling Assessment (Measured in Inches)
Joint |
Right (inches) |
Left (inches) |
Elbow |
8.5 |
8.5 |
Hands |
8.3 |
8.3 |
Feet |
11.3 |
11.5 |
Knees |
16.9 |
16.5 |
Timeline of Clinical Events
Table No. 5 : Clinical Chronology
Sr. No. |
Clinical Events / Complaints |
Duration / Onset |
1 |
Pain, swelling, stiffness in bilateral hands and feet with discoloration |
3 years |
2 |
Pain, swelling, stiffness in bilateral knees and elbows with discoloration |
3 years |
3 |
Intermittent fever |
3 years |
4 |
Anxiety symptoms |
4 years |
5 |
Diagnosis of Hypertension |
2 years |
6 |
ANA Positive |
2022 |
Diagnostic Assessment
Based on the patient’s clinical presentation—including symmetrical joint pain with edema, blackish discoloration, intermittent fever, positive ANA report, and history of autoimmune involvement—the condition was diagnosed as Systemic Lupus Erythematosus (SLE). In Ayurveda, the clinical features were assessed in terms of Vatapradhana Vatarakta, characterized by aggravated Vata obstructed by vitiated Rakta, resulting in musculoskeletal and systemic disturbances.
Therapeutic Intervention
Considering the chronicity of symptoms and the patient’s intolerance to strong Shodhana (purificatory) therapies, a Mridu Shodhana (mild purification) approach was adopted. A classical Virechana Karma followed by Ksheera Basti, as mentioned in the Siddhi Sthana of Charaka Samhita, was implemented.
Table 6: Virechana Karma Protocol
Sr. No. | Modality | Drug | Dose | Anupana | Time of Administration | Duration |
1 | Deepana–Pachana | Aampachaka Vati | 2 tablets | Lukewarm water | Twice daily before meals | 5 days |
2 | Snehapana (Internal oleation) | Go-Ghrita | Started with 30 ml up to 220 ml | As needed with lukewarm water | Morning (7:00–7:30 AM) | 5 days |
3 | Sarvanga Abhyanga (massage) | Bala Taila | Q.S. | — | — | 4 days |
4 | Sarvanga Bashpa Swedana | — | — | — | — | 4 days |
5 | Virechana Karma (purgation) | Aragvadhadi Avaleha | 100 gm | Lukewarm water | After Shleshma Kala (~10:30 AM) | 1 day |
6 | Samsarjana Krama (dietary regimen) | — | As per Madhyama Shuddhi | — | Upon onset of hunger post Virechana | 5 days |
Ksheera Basti Protocol
Ksheera Basti is considered a Mridu Niruha Basti, suitable for patients where Vamana and other Shodhana therapies are contraindicated. It provides both nutritional and therapeutic benefits and is particularly beneficial in Vata-Rakta conditions.
Table 7 : Ksheera Basti Ingredients
Sr. No. | Modality | Drug/Formulation | Dose/Quantity | Duration |
1 | Sthanik Abhyanga | Sahachara Taila | Q.S. | 8 days |
2 | Sthanik Nadi Swedana | Dashamoola Kwatha | — | 8 days |
3 | Ksheera Basti Mixture | Honey: 80 g | As above composition | 8 days |
Follow-Up and Outcomes
The patient remained hospitalized for 28 days during which Virechana and Ksheera Basti therapies were completed. Notable clinical improvements were observed, particularly in joint pain, stiffness, and swelling, with increased functional mobility. All clinical examinations were repeated post-treatment, showing moderate to marked symptomatic relief.
At discharge, the patient was counselled regarding the chronic and relapsing nature of the disease and was advised to:
- Maintain regular follow-up (every 1 month)
- Avoid dietary and lifestyle factors aggravating Vata and Rakta
- Follow Dinacharya and Ritucharya tailored to her constitution
Table 9. Pain Assessment (VAS Score)
Site of Pain | Before Virechana | After Virechana | After Ksheera Basti | After Follow-up | Site of Pain |
Bilateral Elbows | 9 | 5 | 3 | 0 | Bilateral Elbows |
Bilateral Hands | 9 | 6 | 2 | 0 | Bilateral Hands |
Bilateral Feet | 10 | 7 | 4 | 1 | Bilateral Feet |
Bilateral Knees | 10 | 7 | 3 | 1 | Bilateral Knees |
Table 10. Assessment of Joint Stiffness (Grading System)
Stiffness Grade | Description | Before Virechana | After Virechana | After Ksheera Basti | After Follow-up |
0 | No stiffness | 0 | — | — | — |
1 | Mild (able to perform daily routine without difficulty) | 0 | — | 1 | 1 |
2 | Moderate (difficulty performing daily activities) | 0 | 2 | — | — |
Table 11. Assessment of Swelling (Measured in Inches)
Joint Area | Side | Before Virechana | After Virechana | After Ksheera Basti |
Elbow Joints | R | 8.5 | 8.1 | 8.0 |
| L | 8.5 | 8.2 | 8.0 |
Hands | R | 8.3 | 8.0 | 7.5 |
| L | 8.3 | 7.9 | 7.4 |
Feet | R | 11.3 | 10.1 | 9.5 |
| L | 11.5 | 10.4 | 9.4 |
Knee Joints | R | 16.9 | 16.1 | 15.0 |
| L | 16.5 | 15.6 | 14.9 |
Discussion
The clinical manifestation of Systemic Lupus Erythematosus (SLE) in this case—including pain, stiffness, joint swelling, intermittent fever, and blackish discoloration—can be appropriately correlated with Vatapradhana Vatarakta in Ayurvedic classics. Symptoms such as Dhamani Anguli Sandhinam Sankocha, Atiruk, Karshnya, Shyava Varna Shotha, Kunchana, and Sthambhana align with the observations in this case[5].
Given the Vata-Rakta Dushti and chronicity of symptoms, along with a background of long-term steroid use, a Mridu Shodhana [6] approach was warranted. Virechana Karma using Aragvadhadi Avaleha[7] was selected as it is Snigdha and suitable for Sukumara Purusha and Vata-predominant disorders.
Charaka has described Ksheera Basti (milk-based enema) as the prime line of treatment in Vatarakta. The chosen decoctions—Dashamoola and Punarnavashtaka — possess anti-inflammatory (Shothahara) and analgesic (Shulahara) properties. They are also effective in Raktaprasadana and Twakdoshahara.
- Guduchi, known as the Agryadravya in Vatarakta[8], was used both in Ghrita[9] and Kalka forms. It has Tikta Rasa, Rasayana action[10], and helps pacify Tridoshas.
- Madhu and Saindhava, due to their Yogavahi nature, enhance absorption and bioavailability of the Basti Dravyas.
- The combined effect of Basti Karma significantly reduced symptoms by clearing vitiated Vata and nourishing affected tissues.
This integrative approach proved effective in managing autoimmune inflammation by providing subjective relief, improving joint function, and enhancing quality of life.
Patient Perspective
The patient expressed satisfaction and gratitude with the outcome of the treatment. She was particularly relieved by the rapid reduction in symptoms and regained her ability to perform daily tasks. She acknowledged the seriousness of the illness only after understanding its autoimmune nature post-discharge and appreciated the effectiveness of Ayurveda in managing her chronic condition.
Conclusion
SLE, an autoimmune multisystemic disorder, can be effectively correlated with Vatapradhana Vatarakta in Ayurveda. The integrative Ayurvedic protocol involving Mridu Virechana with Aragvadhadi Avaleha followed by Ksheera Basti prepared with Dashamoola, Punarnavashtaka, and Guduchi formulations resulted in significant symptomatic relief.
Though there was no remarkable change in laboratory parameters, subjective clinical improvement was substantial, underlining the efficacy of Ayurvedic interventions in chronic autoimmune conditions.
Informed Consent
Written informed consent was obtained from the patient for publication of this case report and accompanying data.
References:
[1] Malaviya, A. N., Singh, R. R., Singh, Y. N., Kapoor, S. K., & Kumar, A. (1993). Prevalence of Systemic Lupus Erythematosus in India. Lupus, 2(2),115-118.
[2] Carakasamhita, Cikitsasthana, Vatashonitachikistam, 29/2. Available from http://niimh.nic.in/ebooks/ecaraka/ (Accessed on 15/04/2025)
[3] Carakasamhita, Cikitsasthana, Vatashonitachikistam, 29/10-11. Available from http://niimh.nic.in/ebooks/ecaraka/ (Accessed on 15/04/2025)
[4] Carakasamhita, Cikitsasthana, Vatashonitachikistam, 29/7. Available from http://niimh.nic.in/ebooks/ecaraka/ (Accessed on 15/04/2025)
[5] Carakasamhita, Cikitsasthana, Vatashonitachikistam, 29/24. Available from http://niimh.nic.in/ebooks/ecaraka/ (Accessed on 15/04/2025)
[6] Carakasamhita, Cikitsasthana, Vatashonitachikistam, 29/41. Available from http://niimh.nic.in/ebooks/ecaraka/ (Accessed on 15/04/2025)
[7] Carakasamhita, Kalpasthana, Chaturangulakalpa, 08/12. Available from http://niimh.nic.in/ebooks/ecaraka/ (Accessed on 15/04/2025)
[8] Carakasamhita,Sutrasthana, Vatashonitachikistam, 29/88. Available from http://niimh.nic.in/ebooks/ecaraka/ (Accessed on 15/04/2025)
[9] Chakradatta of Sri Chakrapanidatta with Vaidayprabha Hindi commentry by Dr.Indradeva Tripathi, Chaukhambha Sanskrit Sansthan Varanasi ,Third Edition 1997 Amavatacikitsa verse -58,page 170.
[10] Carakasamhita, Sutrasthana, Deerghanjiviteeya, 1-3/30. Available from http://niimh.nic.in/ebooks/ecaraka/ (Accessed on 15/04/2025).