Analytical Evaluation And Quality Control Parameters For Lipid Based Ayurvedic Formulations: A Comprehensive Review
DOI:
https://doi.org/10.63247/3048-7390.vol.1.issue5.6Keywords:
Sneha Kalpana, Ayurvedic medicine, Quality control, Sneha Paka, Tila TailaAbstract
Introduction:
In Ayurveda, oil and fat-based formulations, known as Sneha Kalpana, are extensively used for treating various ailments. These formulations often face quality degradation due to oxidation, leading to unpleasant odors and health risks. Therefore, establishing robust quality control parameters is crucial to ensure the safety, efficacy, and consistency of these formulations. This review focuses on the analytical techniques and tests employed for quality control of Ayurvedic lipid-based formulations.
Methods:
The review compiles and discusses various physical, chemical, and contaminant-related quality control parameters used to evaluate oil and fat-based Ayurvedic formulations. Methods such as refractive index measurement, congealing point, iodine value, acid value, peroxide value, saponification value, and fatty acid composition analysis are reviewed. Additionally, tests for contaminants like heavy metals, aflatoxins, and pesticide residues are covered. Analytical techniques, including HPTLC, HPLC, GC, and gas-liquid chromatography, are also explored for identifying and quantifying active compounds.
Results:
The review summarizes various tests critical for maintaining the quality of Ayurvedic oils and fats, such as the Baudouin test for sesame oil and the Polybromide test for mustard oil. It provides insights into the effects of oxidation on lipid-based formulations, including changes in fatty acid composition and the formation of secondary oxidation products, which affect product quality. The study also highlights the significance of analyzing contaminants and the importance of compliance with regulatory standards.
Discussion:
The study emphasizes the necessity of implementing rigorous quality control measures in the production of Ayurvedic oil-based formulations to ensure product consistency and safety. By adopting modern analytical techniques and expanding chemical parameters, the standardization of these formulations can be achieved. The integration of new quality control measures, including tests for secondary oxidation and active compounds, will contribute to improving the safety, efficacy, and global acceptance of Ayurvedic products.
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