An Ayurvedic Approach to Granulomatous Uveitis– A Case Study
DOI:
https://doi.org/10.63247/3048-7390.vol.1.issue5.2Keywords:
Granulomatous Uveitis, Ayurvedic Treatment, Sashopha Akshipaka, JalokaavacharanaAbstract
Introduction:
Granulomatous uveitis is an inflammatory condition of the uveal tract characterized by granuloma formation, which can arise from infectious or non-infectious causes. It is often associated with systemic diseases and may lead to vision impairment, especially in cases involving posterior uveitis. Treatment is complex, requiring a multifaceted approach to manage both the underlying cause and inflammation. While conventional therapies typically include corticosteroids, immunosuppressants, and antimicrobial agents, Ayurvedic approaches have also been explored for managing granulomatous uveitis. This case study examines the impact of Ayurvedic treatment on a patient with bilateral non-infective granulomatous posterior uveitis.
Methods:
A 29-year-old female patient with a history of bilateral non-infective granulomatous posterior uveitis and vitritis, unresponsive to conventional steroid therapy, was treated with Ayurvedic interventions. These included Shodhana (purification therapies), Snehapana (medicated ghee), Sarvanga Abhyanga (full-body massage), Virechana (purgation), and topical treatments like Netra Parisheka (eye wash) and Nasya (nasal therapy). Internal Ayurvedic medicines, including Panchatikta Guggulu Ghruta, were prescribed along with supportive therapies. Follow-up assessments were conducted to evaluate visual acuity and symptom relief.
Results:
The patient demonstrated significant improvement in visual acuity, with the left eye achieving 6/12 vision and the right eye improving to 6/36 with pinhole correction. Symptom relief was also noted, with reductions in eye redness, lacrimation, and floaters. These improvements were sustained over follow-up periods, with no recurrence of major symptoms, indicating positive outcomes from the Ayurvedic treatment approach.
Discussion:
The Ayurvedic approach to managing granulomatous uveitis, focusing on holistic treatments like purification and internal medicines, showed promising results in this case. The improvement in visual acuity and symptom management suggests that Ayurvedic treatments may offer an effective adjunct to conventional therapy, particularly in cases where standard treatments are inadequate or contraindicated. However, further controlled studies are needed to validate these findings and assess the long-term efficacy of Ayurvedic treatments for uveitis.
References
1. Tsirouki T, Dastiridou A, Symeonidis C, Tounakaki O, Brazitikou I, Kalogeropoulos C, Androudi S. A Focus on the Epidemiology of Uveitis. Ocul Immunol Inflamm. 2018;26(1):2-16. [PubMed
2. Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, Ivanov S, Duan Q, Bala S, Condon T, van Rooijen N, Grainger JR, Belkaid Y, Ma'ayan A, Riches DW, Yokoyama WM, Ginhoux F, Henson PM, Randolph GJ. Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity. 2013 Sep 19;39(3):599-610. [PMC free article] [PubMed]
3. Crouser ED, White P, Caceres EG, Julian MW, Papp AC, Locke LW, Sadee W, Schlesinger LS. A Novel In Vitro Human Granuloma Model of Sarcoidosis and Latent Tuberculosis Infection. Am J Respir Cell Mol Biol. 2017 Oct;57(4):487-498. [PMC free article] [PubMed]
4. Locke LW, Schlesinger LS, Crouser ED. Current Sarcoidosis Models and the Importance of Focusing on the Granuloma. Front Immunol. 2020;11:1719. [PMC free article] [PubMed]
5. Broos CE, van Nimwegen M, Hoogsteden HC, Hendriks RW, Kool M, van den Blink B. Granuloma formation in pulmonary sarcoidosis. Front Immunol. 2013 Dec 10;4:437. [PMC free article] [PubMed]
6. Rao NA. Pathology of Vogt-Koyanagi-Harada disease. Int Ophthalmol. 2007 Apr-Jun;27(2-3):81-5. [PubMed]
7. 43.
8. PaÇKisaarslan A, SÖzerİ B, Şahİn N, ÖzdemİrÇİÇek S, GÜndÜz Z, Demİrkaya E, Berdelİ A, Sadet Özcan S, PorazoĞlu H, DÜŞÜnsel R. Blau Syndrome and Early-Onset Sarcoidosis: A Six Case Series and Review of the Literature. Arch Rheumatol. 2020 Mar;35(1):117-127. [PMC free article] [PubMed]
9. Rosé CD, Doyle TM, McIlvain-Simpson G, Coffman JE, Rosenbaum JT, Davey MP, Martin TM. Blau syndrome mutation of CARD15/NOD2 in sporadic early onset granulomatous arthritis. J Rheumatol. 2005 Feb;32(2):373-5. [PubMed]
10. https://rarediseases.org/rare-diseases/posterior-uveitis/
11. A K Khurana. Comprehensive ophthalmology, 6thedition. New Delhi Jaypee Brothers Medical publishers (P) limited; reprint 2015, pg 150.
12. Babu BM, Rathinam SR. Intermediate uveitis. Indian J Ophthalmol. 2010 Jan-Feb;58(1):21-7. [PMC free article] [PubMed.
13. Myron Yanoff, MD and Jay S. Duker, MD.Ophthalmology, 4th Edition ISBN : 9781455739844 : Publication Date : 16-12-2013.

Additional Files
Published
Issue
Section
License
Copyright (c) 2025 International Journal of Ayurveda360

This work is licensed under a Creative Commons Attribution 4.0 International License.